VP/Senior Director, Clinical Operations
On-siteSouth San Francisco, California, United States
Job Summary
Orchestrate and manage clinical trials for reprogramming medicines by leading execution through protocol development, CRO selection, and startup activities across US, AUS/NZ, EU, and UK geographies. Collaborate with clinical development to optimize trial designs for patient benefit and cost-efficiency while managing company-wide timelines, budgets, and operational metrics. Disentangle operational challenges including recruitment, cross-border logistics, regulatory compliance, and staffing to ensure delivery. Build and manage a bar-raising clinical operations team as the founding member while supporting regulatory submissions and global compliance obligations.
Required Qualifications
- 10+ years of industry experience in Clinical Operations
- Bachelor's or advanced degree in the life sciences
- History of orchestrating clinical trials through CRO partners with accountability for operational delivery
- Recent experience managing first-in-human trials
- Experience managing trials across multiple geographies (US, AUS, NZ, EU, UK, Japan)
- Quantitative mindset — you track metrics, report numbers rather than anecdotes, and drive for measurable improvements quarter-over-quarter
- Experience managing clinical trial budgets, forecasts, and resource planning
Desired Qualifications
- Recent experience coordinating first-in-human trials in Australia and New Zealand
- Experience managing trials in metabolic disease and hepatology
- Experience recruiting a clinical operations team on a short time horizon
- History of developing nucleic acid medicines (mRNA, ASO, siRNA) and lipid nanoparticle (LNP)-vectored products
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