Subject Matter Expert Solid State Science
On-siteBasel, Basel-City, Switzerland
Job Summary
Lead the identification of optimal solid-state forms for early-stage drug candidates, ensuring necessary solubility and stability for clinical success. Serve as the central hub coordinating complex screening and characterization activities across internal labs and global external partners. Act as the single point of accountability for solid-state strategy, overseeing the lifecycle management of materials from initial biopharmaceutical assessments to final crystallization process definition. Orchestrate cross-functional efforts between Chemistry, Analytics, and Formulation teams to de-risk candidates and define the "Golden Form." Spearhead the evaluation and selection of global external CRO/CMO partners, governing scientific methodologies and ensuring data generation meets rigorous quality standards. Champion the adoption of digitalization and automated screening tools to enhance data analysis throughput and accelerate project cycle times.
Required Qualifications
- Ph.D. in Pharmaceutical Sciences, Chemistry, Material Science, or a related field
- strong focus on solid-state characterization and crystallization
- Deep understanding of solid-state analytical techniques (e.g., XRD, DSC, TGA, DVS, Microscopy)
- application of solid-state analytical techniques in a pharmaceutical development context
- Proven ability to lead complex projects in a matrix environment
- communication skills necessary to translate technical data into strategic decisions for non-expert stakeholders
- Experience managing external CRO/CMO relationships
- track record of driving process improvements
- implementing digital solutions
- proactive, solution-oriented approach
- ability to manage diverse interfaces
- adapt to an evolving, fast-paced R&D environment
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