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CalyxoPosted 2 months ago

Staff Systems Engineer - Pleasanton, CA

$195,000–$205,000 year

On-sitePleasanton, California, United States

Full TimeSenior LevelSmallHEALTHCARE

Job Summary

Architect, validate, and own the system-level behavior of a complex medical device ecosystem throughout the entire product development lifecycle. Define end-to-end system architecture, translate user needs into robust requirements, and drive architectural trade studies using bench testing and prototyping to de-risk critical technical challenges. Lead identification and mitigation of system-level risks, ensure complete traceability from user needs through verification, and serve as the systems subject-matter expert across mechanical, electrical, firmware, software, clinical, and quality teams. Provide clear technical direction to external development partners and mentor engineers on systems thinking and architectural rigor.

Required Qualifications

  • Bachelor's degree in Mechanical Engineering, Biomedical Engineering, or related field
  • 12+ years of experience in medical device development
  • significant ownership of system architecture
  • Strong hands-on experience with both: Single-use disposable systems, Capital equipment incorporating pumps, sensors, and closed-loop control
  • Experience architecting systems that integrate hardware, disposables, and software
  • Proven ownership of system-level requirements and verification
  • Proficiency with Jama (or equivalent), dFMEAs, fault-tree analysis, and requirements traceability
  • Strong working knowledge of relevant medical device standards (e.g., ISO 14971, IEC 62304, IEC 60601 family)
  • Track record of writing high-quality, testable requirements that scale across complex systems
  • Staff-level technical judgment and decision-making capability
  • Ability to lead through influence and technical authority rather than direct reporting lines
  • Clear, concise technical communicator across disciplines and experience levels
  • Comfortable operating in ambiguity, making informed trade-offs, and driving alignment
  • Location: Pleasanton, CA (on-site presence expected 4–5 days per week)
  • Travel: Minimal (<10%)
  • Legal authorization to work in the United States

Desired Qualifications

  • Master's or PhD

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