Sr. Scientist, Neuroimmunology
$119,100–$187,500 year
On-siteBoston, Massachusetts, United States
EXPIREDBoston, Massachusetts, United StatesOn-siteFull Time$119,100–$187,500 yearSenior LevelDoctorate Or Professional DegreeEnterprise
Full TimeSenior LevelDoctorate Or Professional DegreeEnterprise
Job Summary
Design and execute in vivo studies to generate mechanistic insights into microglial biology and CNS immune cell isolation. Interpret complex datasets from pharmacology, efficacy, biomarker, and molecular profiling to support target validation and drug discovery programs. Collaborate with multidisciplinary teams across pharmacology, immunology, chemistry, and data science to communicate findings and influence decision-making through data-driven recommendations. Provide scientific leadership and contribute to program strategy for neurodegenerative disease therapies.
Required Qualifications
- PhD in Neuroscience, Immunology, Cell Biology, Pharmacology, Bioengineering, Neurology, or a related STEM field
- Master's degree in Neuroscience, Immunology, Cell Biology, Pharmacology, Bioengineering, Neurology, or a related STEM field
- Minimum 6+ years of pharmaceutical or biotechnology industry experience
- Extensive hands-on experience with rodent in vivo studies
- Experience with mouse models of neurodegeneration, neuroinflammation, or CNS disease
- Expertise in flow cytometry, CNS immune cell isolation, immunohistochemistry, and molecular biology techniques
- Familiarity with omics approaches (RNA-seq, single-cell technologies) and data analysis
- Strong experimental design, statistical analysis, and problem-solving skills
- Excellent communication and collaboration skills in a cross-functional research environment
- Valid driving license
Desired Qualifications
- Postdoctoral industry experience
- Industry experience supporting discovery or early development programs in CNS disorders
- Experience with Alzheimer's disease, Parkinson's disease, ALS, multiple sclerosis, or related neurodegenerative diseases
- Hands-on experience with transgenic rodent models, including behavioral, pharmacology, and biomarker studies
- Experience with primary microglia cultures, macrophages, immune cell assays, or iPSC-derived CNS cell systems
- Familiarity with translational biomarkers, PK/PD relationships, and mechanism-based drug development
- Experience working within multidisciplinary drug discovery teams and advancing programs from target validation through candidate selection
- Prior experience leading collaborative projects, in particular, the ability to coordinate activities across multiple functions
- Highly independent scientist who enjoys working at the bench
- Excels in in vivo experimentation
- Passionate about advancing innovative therapies for neurodegenerative diseases
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