Sr. Scientist II (PRD))
On-siteDurham, North Carolina, United States
Job Summary
Carry out multistep organic syntheses, isolation, and purification of targeted products independently while optimizing routes for purity, reproducibility, scalability, and yield. Proficiently conduct analysis of starting materials, reaction mixtures, intermediates, and products using instrumentation such as NMR, IR, MS, and HPLC. Independently design new synthetic processes for drug substances and generate summaries and reports for internal and external use. Work closely with chemistry, analytical, and manufacturing teams to coordinate activities and assist in crossfunctional process transfers. Conduct laboratory operations safely in compliance with federal, state, and local regulations. Present experimental work internally and externally to clients and regulatory agencies, participating in project team meetings.
Required Qualifications
- Advanced understanding of general chemistry and organic chemistry
- Understanding of modern organic synthesis reactions, isolations and purification procedures
- Full understanding of common synthetic organic reaction mechanisms
- Understanding and proficient use of all relevant analytical techniques and instrumentation such as NMR, IR, MS and HPLC
- Expertise in laboratory glassware and organic chemistry reaction set up, isolation and purification
- Must demonstrate proficiency in synthesis and purification techniques on scales ranging from milligrams to kilograms
- Good written and verbal communication skills
- Familiarity with computer software such as ChemDraw, Microsoft Word, PowerPoint, and Excel
- Good attention to detail and strong problem-solving skills
- Effectively presents ideas and concepts
- S./B.A. in Chemistry with 12 - 15+ years of experience in related industry
- MS in Organic Chemistry with 6 - 8+ years related experience
- Ph.D. in Organic Chemistry with 0 – 3+ years related experience
Desired Qualifications
- Aptitude and willingness to gain more skills & knowledge
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