Sr. Research Associate, Protein Design
$74,000–$118,400 year
Hybrid · Cambridge, Massachusetts, United States
Job Summary
Senior role focusing on mammalian cell culture-based protein expression, purification by chromatography, and biophysical characterization to support vaccine and therapeutic development. Responsibilities include optimizing expression/purification conditions, characterizing proteins using SDS-PAGE, Western blot, DSC/DSF, SEC-MALS, and employing methods like flow cytometry, BLI, and SPR to study biomolecular interactions. Collaborates across groups, interprets and presents experimental data, manages reagent inventories and logistics for partnered programs, and uses agentic AI tools to assist data analysis and presentation.
Required Qualifications
- Bachelor's degree in Biochemistry, Biology, Molecular Biology, or related field
- 2+ years of relevant experience, or Master’s degree with 1+ years of relevant experience
- Hands-on experience with mammalian cell culture techniques for protein expression
- Proficiency in standard methods for recombinant protein expression and purification
- Experience operating and performing basic maintenance on FPLC systems
- Familiarity with biophysical characterization techniques for proteins
- Ability to work on multiple collaborative projects in a cross-functional team environment
- Strong multi-tasking skills and attention to detail
- Excellent written and verbal communication skills
- Prior co-op or internship experience in a protein biochemistry laboratory is preferred
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