Sr Histology Genomics Focused Technician
On-siteCambridge, England, United Kingdom
Cambridge, England, United KingdomOn-siteFull TimeSenior LevelBachelors DegreeEnterprise
Full TimeSenior LevelBachelors DegreeEnterprise
Job Summary
Conduct tissue receipt, embedding, histological sectioning, and TMA construction while performing H&E staining and slide preparation. Process tissue scrapes, annotations, and macrodissection activities for genomics-related projects, then coordinate compliant sample handovers to Genomics teams. Maintain laboratory equipment, document activities in regulated systems, and adhere to GCP, SOPs, and Human Tissue Act requirements. Work within a multidisciplinary team supporting AstraZeneca translational pathology and drug development programmes in Cambridge.
Required Qualifications
- BSc degree in a relevant scientific discipline or equivalent experience
- At least 1 year of experience within histology, translational pathology, tissue-based laboratory operations, or another regulated laboratory environment
- Experience in histological sectioning, tissue handling, and laboratory record keeping
- Experience supporting laboratory equipment maintenance and laboratory operations
- Knowledge of GCP regulations and compliant laboratory practices
- Understanding of regulations governing the ethical use and handling of human tissue samples
- Strong attention to detail with the ability to maintain accurate and compliant records
- Ability to work effectively within a multidisciplinary team
- Commitment to laboratory safety and quality standards
Desired Qualifications
- Experience with Tissue Microarray (TMA) construction and cell pellet processing
- Experience with H&E staining, tissue scrape, tissue annotation, and macrodissection
- Experience supporting genomics-related sample preparation workflows
- Experience working within an HTA-regulated environment
- Familiarity with digital pathology, sample tracking systems, or regulated documentation systems
- Experience supporting audits, inspections, deviations, CAPAs, and change controls
- Knowledge of pathology and translational medicine workflows
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