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Garvan Institute of Medical ResearchPosted 1 month ago

Single Cell Genomics Research Officer/Senior Research Officer

$128,000–$128,000 year

On-siteSydney, New South Wales, Australia

Full TimeSenior LevelLarge

Job Summary

Lead the immunogenomic program by selecting autoimmune diseases for project development and directing primary research using fluorescent sorting, single-cell DNA/RNA sequencing, and whole genome sequencing. Design experiments on patient samples, prepare proposals for competitive funding as lead or co-investigator, and mentor junior staff and students. Oversee assay development and validation while maintaining knowledge of antibody/TCR repertoire analysis and personalized medicine. This two-year fixed-term role within the Goodnow Lab at Garvan expands research into rogue clones across common polyclonal autoimmune diseases, paired with a clinical trials program translating findings into rationally designed trials.

Required Qualifications

  • PhD degree that has been undertaken in a related area of science
  • Extensive experience in key methods including flow cytometry and analysis
  • Extensive experience in cell sorting
  • Extensive experience in single-cell sequencing
  • Extensive experience in RNAseq
  • Extensive experience in whole genome sequencing
  • Extensive experience in PCR
  • Extensive experience in in-vitro cell assays
  • PhD and/or postdoctoral research experience leading to publication of high quality first author and/or senior author and multi-author papers
  • Commitment to scientific excellence and integrity
  • Experience training and mentoring undergraduate and postgraduate students
  • Ability to develop, manage and maintain internal and external collaborations and relationships
  • Highly developed skills in facilitation and meeting leadership
  • Highly developed written and verbal communications skills
  • Strong project management skills
  • Ability to operate independently, develop and troubleshoot assays
  • Full working rights in Australia

Desired Qualifications

  • PhD degree in molecular immunology or genomics
  • Experience in recombinant antibody expression and testing by ELISA
  • Experience in histology (immunohistochemistry and immunofluorescence microscopy)

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