Senior Scientist, Respiratory Discovery

Senior Scientist in Respiratory Discovery leading in vitro and ex vivo studies to support target validation and translational biology across chronic lung diseases. Responsibilities include designing and executing primary airway epithelial culture systems, ALI models, immune assays, and co-culture platforms; generating mechanistic and disease-relevant datasets using molecular, cellular, imaging, and biomarker-based approaches; applying imaging (IHC, IF, high-content imaging) and flow cytometry for immune and cellular phenotyping; supporting translational biomarker discovery with multiplex platforms; conducting cell culture, PBMC isolation, PCR/qPCR, and biomarker assays; characterizing disease-relevant pathways in inflammatory, epithelial, fibrotic, and immune contexts; generating high-quality datasets to inform project decisions; and communicating findings through presentations and reports; collaborating across biology, pharmacology, DMPK, and translational/clinical functions in a matrixed environment.