Senior Scientist I
$100,000–$115,000 year
On-siteCranbury, New Jersey, United States
Job Summary
Conduct advanced metabolite identification and elucidation using liquid chromatography-tandem high-resolution accurate mass spectrometry, NMR, and radioactivity detection. Independently design and execute complicated in vivo and in vitro metabolism studies while handling radio-labeled materials such as 3H and 14C. Lead projects as a study director or principal investigator, managing planning, execution, and delivery of assays for drug discovery and development stages. Write comprehensive reports, present oral findings, and mentor others on technical and business issues. Maintain organized research notebooks, review colleague calculations, and contribute to Standard Operating Procedures. Adhere to regulatory guidance including MIST criteria and company safety policies.
Required Qualifications
- PhD, Master or bachelor's degree in chemistry, Biology, or related science degree
- PhD with 3+ years related experience
- Master's degree with 10+ years related experience
- Bachelor's degree with 13+ years related experience
- equivalent combination of education and/or work experience
- Strong knowledge and experience of experimental methods, concepts and techniques relevant to metabolite identification and profiling, such as in vivo/in vitro sample processing, method development and analysis, structure elucidation and metabolic pathways
- Strong background in organic and analytical chemistry
- extensive experience of interpreting complex mass spectrometry data
- Familiarity with specialized metabolic profiling software
- A good understanding of regulatory guidance like MIST guidance and acceptance criteria in discovery and development stages
- Emerging skills in novel experimental methods, concepts and techniques
- Demonstrate independent thought and scientific creativity
- Demonstrate technical success and proficiency in projects
- Can independently propose and conduct research and develop new methodologies to implement and resolve complex problems
- Effective oral and written communication and interpersonal skills
- Good time management skills to perform multiple projects within timelines
- Ability to work in a team environment
- Follow and adhere to non-GLP guidelines/SOPs consistent with WuXi AppTec requirement
- Must be able to work in an office environment with minimal noise conditions
- Must be able to work in Lab setting with exposure to biohazards / chemicals
- Must be able to wear appropriate PPE
- Must be able to work in environment with variable noise levels
- Ability to stand /Sit/walk for long periods of time
- Ability to push/pull/lLift 15 lbs. routinely
- Ability to crouch, bend, twist, and reach
- Clarity of Vision
- Ability to identify and distinguish colors
- Must be able to perform activities with repetitive motions
- Ability to work in variable temperatures high to freezing
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