(Senior) Scientist –High-resolution Mass Spectrometry
$72,500–$115,230 year
On-siteBeerse, Flanders, Belgium
Job Summary
Design and develop advanced high-resolution mass spectrometry methods for structure elucidation of active pharmaceutical ingredients, with emphasis on peptides, oligonucleotides, and antibody-drug conjugates. Lead comprehensive root cause investigations related to MS-based structure elucidation and independently troubleshoot diverse mass spectrometers. Develop databases, spectral libraries, and in silico tools to facilitate analysis while maintaining compliance with GMP and regulatory frameworks. Collaborate with internal and external specialists to expand innovation networks through university partnerships. This laboratory-based role within Johnson & Johnson's Analytical Development organization supports the Global Therapeutics Development and Supply portfolio in Antwerp, Belgium.
Required Qualifications
- PhD degree in analytical chemistry or related field; or a master's degree in related science with a minimum of 6 years of experience
- Work-related experience in pharmaceutical R&D
- Proven in-depth and hands-on expertise in high-resolution mass spectrometry
- Proven in-depth and hands-on expertise in high-resolution mass spectrometry is essential for this role, particularly with a focus on MS-based structure elucidation
- Excellent English communication skills, both written and spoken, allowing for effective scientific discussions and collaboration
Desired Qualifications
- Experience with coding, programming and the use of in silico tools to assist structure elucidation is a clear plus
- Working experience with mass spectrometry of (cyclic) peptides, oligonucleotides and/or ADCs is an advantage
- Hands-on experience with advanced hyphenated separation technology such as capillary electrophoresis (CE) or multidimensional liquid chromatography is an asset
- Knowledge of regulatory frameworks (e.g., ICH, EMA, FDA) and GMP guidelines, particularly concerning validation requirements, is an advantage
Hiring someone like this?
Get your role in front of qualified candidates on Sorce.