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AmgenPosted 2 weeks ago

Senior Scientist – Functional Genomics

$127,121–$171,988 year

On-siteThousand Oaks, California, United States

Full TimeSenior LevelDoctorate Or Professional DegreeEnterprise

Job Summary

Develop and implement next-generation viral vector platforms and genome engineering technologies to accelerate target discovery and validation. Design, engineer, produce, optimize, and characterize adeno-associated virus and lentiviral vectors for genetic perturbation applications in both in vitro and in vivo model systems. Execute innovative molecular biology experiments supporting target identification, mechanistic studies, and CRISPR-based approaches, analyzing results to communicate biological insights to multidisciplinary teams. Evaluate emerging technologies in functional genomics to enhance discovery capabilities across oncology, inflammation, general medicine, and rare disease therapeutic areas.

Required Qualifications

  • Doctorate degree [and relevant post-doc where applicable]
  • Master's degree and 3 years of scientific experience
  • Bachelor's degree and 5 years of scientific experience
  • Demonstrated expertise in the design, engineering, production, optimization, and characterization of viral vectors—particularly adeno-associated virus (AAV) and lentiviral vectors
  • Expertise in molecular biology, genome engineering, and functional genomics
  • Ability to rapidly develop viral vector engineering capabilities

Desired Qualifications

  • Ph.D. in Molecular Biology, Cell Biology, Genetics, Bioengineering, Virology, or a related discipline with 1–2 years of relevant postdoctoral and/or industry research experience
  • Strong background in molecular biology, genome engineering, CRISPR technologies, and functional genomics
  • Experience applying viral vector technologies to support in vitro and in vivo CRISPR-based genetic perturbation studies
  • Expertise in molecular cloning, construct design, and development of genetic tools
  • Excellent experimental design, data analysis, troubleshooting, communication, and collaboration skills
  • Demonstrated scientific creativity, innovation, and success in a multidisciplinary research environment

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