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MaxCytePosted 2 weeks ago

Senior Scientist, Bioproduction and Bioprocessing

$150,000–$200,000 year

On-siteRockville, Maryland, United States

Full TimeSenior LevelDoctorate Or Professional DegreeSmall

Job Summary

Lead development, optimization, and execution of mammalian cell-based protein production workflows for research, development, and manufacturing needs. Manage stable pool and stable cell line generation, including transfection, clone screening, and productivity assessment using CHOZN, CHOK1-sv, CHOK, and HEK293 cell lines. Develop, optimize, and scale transient protein expression processes for antibodies and recombinant proteins while conducting upstream protein expression studies. Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations. Analyze experimental data, prepare technical summaries, and present results to internal and external stakeholders. Collaborate with downstream purification, analytical development, and project management teams to ensure alignment and timely delivery of materials. Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists. Identify opportunities to enhance bioproduction workflows, including media/feed optimization, vector improvements, and process parameter refinement. Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability. Lead exploratory studies to assess emerging bioprocessing methods and integrate validated improvements into standard workflows. Contribute to internal innovation initiatives, including development of new production strategies, platform enhancements, and scientific capability expansion. Provide technical insight to support long-term bioproduction strategy and organizational growth. Maintain accurate, complete, and compliant laboratory records. Ensure adherence to organizational, regulatory, and safety standards.

Required Qualifications

  • PhD in biological sciences or related field
  • 10+ years of relevant industry experience in bioproduction, bioprocessing, or cell line development
  • Master's degree with 13+ years of experience in bioproduction, bioprocessing, or cell line development
  • Demonstrated expertise in stable cell line development and clone selection
  • Extensive hands-on experience with transient expression of antibodies or recombinant proteins
  • Strong foundation in mammalian cell culture and upstream protein expression
  • Experience with high-throughput screening, automation, or advanced analytical tools
  • Background in cell engineering, vector design, media/feed optimization, or bioprocess development
  • Prior experience in structured, milestone-driven industry or core laboratory environments
  • Good communication skills
  • Ability to work collaboratively with internal team members and customers
  • Ability to travel up to 20%

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