Senior Research Associate 1 (Contract)
$99,840–$99,840 year
On-siteMillbrae, California, United States
Job Summary
Perform high-throughput and supercritical fluid chromatography (SFC) purification of small molecules to support the medicinal chemistry team. Run mass-directed purification using Waters Autopurifier and Agilent systems, including fraction collection based on mass-spectrometry detection. Apply and adapt established chromatographic methods, assist in developing new methods, and perform routine maintenance and troubleshooting of instruments to minimize downtime. Manage large sample sets and associated data accurately, document procedures and results, and compile, analyze, and present purification and analytical data to the team. Contribute to team efforts to improve process efficiency and expand purification applications, while monitoring inventory of consumables to ensure work stays on schedule.
Required Qualifications
- Master's degree with 2 years of experience, or Bachelor's degree with 4 years of related experience, in Chemistry, Analytical Chemistry, Chemical Engineering, or a related field
- Hands-on experience purifying small molecules by reversed-phase HPLC and/or SFC, including fraction collection through mass-spectrometry-based detection
- Familiarity with mass-directed purification, particularly using Waters Autopurifier and Agilent mass-directed purification systems
- Fundamental understanding of the principles of chromatography and the working principles of chromatographic instruments, both analytical and preparative
- Experience working in a high-throughput environment, managing large numbers of samples and the associated data
- Demonstrated problem-solving skills, including routine troubleshooting of instruments and data-management issues
- Proficiency in designing and performing experiments, followed by data compilation and presentation
- Excellent communication skills, both oral and written
Desired Qualifications
- Familiarity with laboratory automation or instrument-specific software is a plus
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