Senior Machine Learning Scientist I, Drug Discovery Analytics
$229,000–$269,000 year
On-siteRedwood City, California, United States
Job Summary
Senior Machine Learning Scientist I to accelerate drug discovery at Revolution Medicines. Develop predictive models to predict compound activity, selectivity, and developability; create predictive frameworks for ADME/Tox and phenotypic outcomes; apply deep learning, graph neural networks, and ensemble methods; collaborate with medicinal chemists and biologists to support target discovery, lead optimization, and translational research; integrate models into discovery pipelines and work with data/ML engineers to deploy solutions. The role emphasizes cross-functional collaboration across chemistry and biology, handling heterogeneous datasets (chemical structures, screening data, molecular simulations), and advancing data-driven discovery through modeling, validation, and deployment. Preferred skills include cheminformatics tools (RDKit, OpenEye), multi-omics analysis, cloud computing, and MLOps for scalable deployment.
Required Qualifications
- PhD in machine learning, computational biology, computational chemistry, computer science, statistics, or a related quantitative field
- 6–10 years of experience applying machine learning or advanced analytics to scientific datasets
- Python and scientific computing libraries (NumPy, Pandas, SciPy)
- Machine learning frameworks (PyTorch, TensorFlow, scikit-learn)
- Model development, validation, and evaluation methods
- Data visualization and exploratory analysis
- Experience working with noisy and incomplete experimental datasets
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