Senior Director, Pharmacokinetics
$194,100–$305,600 year
On-siteSouth San Francisco, California, United States
Job Summary
Provide scientific and portfolio leadership for bioanalytical strategy across discovery programs, ensuring fit-for-purpose assay execution, data quality, and decision-making impact across biologics, conjugates, peptides, small molecules, and emerging modalities. Drive operational excellence through workflow optimization, resource planning, automation, and continuous improvement of bioanalytical processes. Manage a team of bioanalytical leaders and scientists, setting clear expectations and enabling effective prioritization and career development. Represent PDMB on cross-functional discovery and development teams, integrating bioanalytical, ADME, PK/PD, and regulatory perspectives to guide program decisions. Monitor external scientific and regulatory trends to champion new methodologies and best practices. Review, author, and present scientific documents and portfolio updates for internal and external stakeholders.
Required Qualifications
- Master's (with 15+ years) or Ph.D. (with 12+ years) in pharmacokinetics, pharmaceutical sciences, bioanalytical chemistry, analytical chemistry, biochemistry, biology, pharmacology, immunology, bioengineering, or a related scientific discipline
- significant experience in bioanalytical sciences
- experience in DMPK
- experience in drug discovery and development
- Demonstrated scientific and operational leadership in bioanalysis
- Track record demonstrating strong understanding of bioanalytical approaches relevant to biologics, conjugates, peptide, small molecule, and novel therapeutic modalities
- Proven experience participating in cross-functional discovery and development program teams
- Proven ability to integrate bioanalytical, ADME, PK, PK/PD, translational, toxicology, clinical pharmacology, and regulatory considerations to support program decisions
- Demonstrated ability to manage a portfolio of programs by early strategy formation, prioritizing resources, aligning deliverables with milestones, identifying risks, and ensuring high-quality scientific execution
- Demonstrated ability to develop DMPK representatives, bioanalytical leaders/scientists by strengthening scientific judgment, project-team leadership, communication, and decision-making impact
- Proven people leadership experience, including management, mentoring, talent development, performance management, and building high-performing scientific teams
- Demonstrated ability to lead through change, shape organizational capabilities, and develop future scientific and people leaders
- Excellent written and verbal communication skills
- Strong collaboration and influencing skills
- Commitment to quality, safety, compliance, scientific rigor, operational excellence, and inclusive leadership
- Valid Driving License
Desired Qualifications
- Demonstrated ability to modernize workflows through automation, digital tools, data systems, assay harmonization, process improvement, or innovative bioanalytical technologies
- Experience serving as scientific representative, or functional leader accountable for cross-function and/or cross-site collaboration
- Familiarity with translational PK/PD, exposure-response, human dose projection, biomarker strategy, biodistribution assessment, immunogenicity risk assessment, or model-informed drug development
- Experience supporting or leading programs involving drug conjugates, multispecific biologics or peptides, or other complex and emerging modalities
- Working knowledge of cell-based assays, biophysical or biochemical characterization
- Track record of scientific visibility through publications, conference presentations, external collaborations, consortia participation, or cross-industry engagement
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