Senior Director of Clinical Science - Lung
$190,800–$300,300 year
HybridBoston, Massachusetts, United States or South San Francisco, California, United States
Job Summary
Lead strategic Clinical Science leadership across the lung disease area, including multiple studies, programs, and assets. Contribute to disease area strategy by providing input on development opportunities, scientific considerations, and portfolio risks. Partner with Section Heads, Asset Leads, and cross-functional leaders to support alignment of Clinical Science activities with broader program objectives. Standardize Clinical Science approaches, including medical data review practices and data interpretation principles, while advocating for innovative workflows. Provide senior scientific guidance to support high-quality input and guide interpretation of clinical data across studies and cohorts. Contribute Clinical Science perspective to portfolio discussions, governance reviews, and senior leadership meetings. Provide direct management for Directors, Principal Scientists, and Clinical Scientists, setting clear expectations and fostering talent development. Collaborate closely with Clinical Operations, Regulatory Affairs, Biostatistics, Drug Safety, and other partner functions to facilitate alignment and effective portfolio execution.
Required Qualifications
- Advanced scientific or healthcare degree (PhD, PharmD)
- Master's Degree in life sciences
- At least 7 years of lung oncology drug development experience
- At least 12 years of lung oncology drug development experience
- Significant experience in Clinical Development, Clinical Science, oncology development, or a related function within the pharmaceutical or biotechnology industry
- Demonstrated experience providing Clinical Science leadership across multiple studies, programs, or assets
- Deep therapeutic area expertise in lung cancer, including strong understanding of disease biology, current and emerging treatment landscape, clinically relevant endpoints, and key scientific considerations affecting development
- Strong understanding of clinical trial design, clinical development strategy, clinical data review, and interpretation of oncology data
- Experience contributing to disease area strategy, portfolio discussions, or cross-program planning
- Experience contributing to regulatory submissions, safety reviews, or health authority interactions
- Experience working effectively in cross-functional teams within a matrix environment
- Demonstrated ability to integrate information across studies and programs to support scientific and business decisions
- Excellent communication, influence, and executive presentation skills
- Demonstrated people leadership experience, including management, coaching, and development of scientific staff
- 0-25% travel
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