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BiogenPosted 3 weeks ago

Scientist, Neuromuscular Research

$111,000–$144,000 year

On-siteCambridge, Massachusetts, United States

Full TimeDoctorate Or Professional DegreeLarge

Job Summary

Independently design, execute, analyze, and interpret experiments supporting neuromuscular research programs. Develop and optimize molecular and cellular assays in iPSC-derived and primary human skeletal and cardiac disease models to assess therapeutic activity and mechanism of action. Characterize muscle disease relevant phenotypes in rodent models, including in vivo muscle function assessment. Present data clearly and concisely in team meetings and cross-functional forums while collaborating with internal teams and external partners to facilitate research progress. Requires a PhD with hands-on experience in muscle biology, biochemistry, and molecular techniques. Base compensation ranges from $111,000 to $144,000, with eligibility for short and long-term incentives. Biogen offers a full benefits package including medical, dental, vision, 401(k) matching, tuition reimbursement, and paid time off.

Required Qualifications

  • PhD with 0-2+ years of relevant academic or industry experience in muscle biology, physiology, or a related field
  • Strong scientific and technical background in muscle biology, disease pathophysiology, and translational research
  • Demonstrated hands-on experience with the following techniques: iPSC-derived and primary human myotube and cardiomyocyte culture
  • In vivo muscle function assessment, including evoked force measures, treadmill and other relevant endpoints in neuromuscular disease models
  • Biochemistry and molecular biology techniques
  • Statistical analysis using GraphPad Prism or similar data analysis software
  • Ability to independently design, execute and trouble shoot experiments
  • Excellent presentation and communication skills

Desired Qualifications

  • Strong scientific background in muscle biology and/or genetic neuromuscular disorders such as DMD and DM1
  • Direct experience with RNA therapies, antisense oligonucleotides, LNP
  • Strong track record of scientific publications and presentations

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