Scientist II, Bioinformatics QC
$129,600–$158,400 year
On-siteSan Diego, California, United States
Job Summary
Execute bioinformatics QC analyses across multi-omics assays including RNA-seq, WGS, and structural variation to support product quality assessment and release. Analyze and interpret data against established acceptance criteria, escalate atypical results, and prepare compliant documentation for audit readiness. Collaborate with QC, QA, Manufacturing, and R&D teams to support sample processing timelines, while contributing to root cause analysis, workflow optimization, and pipeline validation activities. This on-site role in Torrey Pines, CA, requires flexibility for weekend and holiday work and involves exposure to laboratory chemicals. Candidates must hold a PhD in a relevant field with hands-on NGS pipeline experience and familiarity with GMP environments.
Required Qualifications
- PhD in Bioinformatics, Genomics, Computational Biology, or related field (or equivalent combination of education and relevant experience)
- Hands-on experience with NGS data analysis pipelines (RNA-seq, WGS, or similar)
- Experience working in drug development or other regulated environments (GMP/GxP), including understanding of data integrity expectations
- Strong understanding of human genetics and genomics, including variant analysis, gene expression, and structural variation in applied settings
- Proficiency in scripting and data analysis tools (e.g., Python, R, Bash) to support reproducible workflows
- Excellent attention to detail with demonstrated ability to produce accurate, high-quality, and traceable datasets
- Familiarity with QC and QA workflows, documentation practices, and audit readiness requirements
- Ability to interpret biological and genomics data in clinical or translational contexts to support QC decision-making
- Strong written and verbal communication skills, with the ability to clearly document and explain analytical methods and results
- Comfort working with ambiguity and applying scientific reasoning to analyze and troubleshoot real-world datasets
- Exposure to qualification and validation of bioinformatics systems and pipelines in regulated environments
- Ability to contribute to the design, improvement, and scaling of bioinformatics workflows and organizational systems
- Valid work authorization that does not require employer sponsorship now or in the future
Desired Qualifications
- Flexibility and availability for weekend and holiday work as needed
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