Scientist I, In Vitro Technologies - Discovery Biotherapeutics
$75,000–$142,500 year
On-siteWorcester, Massachusetts, United States
Job Summary
Design and execute in vitro display technologies for lead antibody identification and optimization. Collaborate to generate stage-gate appropriate in vitro, cellular, and in vivo data packages supporting proof-of-concept. Develop and implement research supporting the discovery, optimization, and mechanistic understanding of molecular pharmacology across therapeutic areas. Analyze, document, and report data effectively while presenting findings in group settings to internal and external scientific leaders. Manage multiple projects simultaneously in a fast-paced, multi-disciplinary environment. This Scientist I role joins Discovery Biotherapeutics and Genetic Medicine at AbbVie to drive biologics drug discovery and engineering. The position focuses on leveraging scientific expertise to advance therapeutic molecules across immunology, oncology, and neuroscience.
Required Qualifications
- BS or MS in Biology or a related field
- 5+ years of experience (BS)
- 2+ years of experience (MS)
- Strong molecular biology skills (e.g., molecular cloning)
- Familiarity with sequence analysis tools (e.g., Geneious, Genedata, PipeBio)
- Experience with biologics, antibodies, antibody fragments, and mimetics
- Experience with bacterial cell culture
- Solid understanding of protein structure and function
- Excellent oral and written communication skills
- Ability to engage internal and external scientific leaders in collaborative research
- Strong organizational skills with the ability to manage multiple projects simultaneously
- Team player who thrives in a fast-paced, multi-disciplinary environment
- Ability to adapt to rapid changes in project priorities and timelines
- Proficiency with MS Office Suite (Excel, PowerPoint, Word)
Desired Qualifications
- Hands-on experience with in vitro antibody discovery display technologies (e.g., phage display, yeast display)
- Direct experience with binding assays (e.g., ELISA, flow cytometry)
- Experience in antibody engineering and optimization (e.g., affinity modulation, liability engineering, humanization)
- Experience with antibody library design and construction
- Experience with mammalian cell culture
- Experience with automation of biologics discovery processes
- Proficiency with Prism, Geneious, Sequencher, and/or Genedata
- Familiarity with computational approaches and an ability to work independently and in partnership with AI/ML and Digital Transformation teams to amplify in vitro technology workflows and contribute to AbbVie's AI/ML infrastructure
Hiring someone like this?
Get your role in front of qualified candidates on Sorce.