Scientist I
$128,000–$142,000 year
On-site · Redwood City, California, United States
Job Summary
The Scientist I will develop and optimize enzymatic synthesis processes for therapeutic RNA oligonucleotides, advancing process design and optimization within the Process Chemistry department. Responsibilities include screening starting materials, developing bench- and pilot-scale unit operations (nanofiltration, purification, ultrafiltration, depth filtration), troubleshooting with commercial/project teams, leading multidisciplinary teams, supervising technical staff, and evaluating new ECO synthesis technologies. The role requires strong foundational knowledge in chemistry/chemical engineering and practical experience with enzyme physiology, data analysis (DOE), and flow-based reactor systems; experience with process development and scale-up in pharma GMP facilities is valuable.
Required Qualifications
- Ph.D. in Chemistry, Chemical Engineering, Biochemistry, or related discipline with 0-3 years of relevant industrial experience; or B.S. with at least 10 years relevant industrial experience.
- Strong knowledge of chemistry, chemical engineering, enzyme physiology coupled with practical knowledge of process engineering flow applications.
- Experimental design and data analysis capabilities including Design of Experiments (DOE).
- Unicorn software, cGMP regulation understanding and flow-based reactor system use is ideal.
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