Research Associate, Process Development
$87,600–$136,875 year
On-site · Boulder, Colorado, United States
Job Summary
Leads the preparation of milligram to gram quantities of active pharmaceutical ingredient (API) to support early-stage (Pre-clinical) development and toxicology studies; develops synthetic routes, methods, and techniques for oligonucleotide synthesis and purification; ensures cGMP/SOP compliance; documents analyses and writes technical reports to support technology transfer and CMC submissions; designs and executes DOE and PAR experiments to understand design space and process validation; conducts scale-up and process transfer to GMP manufacturing; collaborates on cross-functional projects and stays current with trends in oligonucleotide analytical methods and synthesis development.
Required Qualifications
- Bachelor’s or Master’s Degree in chemistry, chemical engineering, science or equivalent
- 4+ years relevant experience
- Previous knowledge of oligonucleotide synthesis, purification, ultrafiltration, conjugation, and lyophilization
- Detail-oriented and can perform technical duties following SOPs and general laboratory safety rules
- Ability to work both independently and in a team setting
- Excellent math, documentation, communication and operational troubleshooting skills
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