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ProlaioPosted 2 months ago

Product Manager, Clinical Endpoints

$159,000–$159,000 year

On-siteChicago, Illinois, United States

Full TimeSmall

Job Summary

Own the full menu of clinical endpoints our platform offers sponsors, deciding what to build, buy, or partner for based on real sponsor and therapeutic-area needs. Maintain a prioritized roadmap sequencing investments by clinical impact, demand, and feasibility while tracking the evolving landscape of digital biomarkers, novel sensors, and regulatory expectations. Define data collection requirements from medical devices and wearables, weighing signal fidelity and patient burden, then partner with Data Science and Clinical to turn raw signals into validated digital biomarkers. Curate the wider endpoint set including lab-based biomarkers, ePRO, and eCOA, ensuring each measure meets FDA and EMA standards through rigorous analytical and clinical validation. Translate dense scientific requirements into clear buildable specs and engage directly with trial sponsors to align the roadmap with their evolving needs.

Required Qualifications

  • 8+ years in product management, clinical science, or endpoint/measurement roles in Digital Health, MedTech, or Life Sciences
  • Deep familiarity with clinical trial endpoints across modalities—digital measures, wearable and sensor data, lab-based biomarkers, and ePRO/eCOA
  • Hands-on experience taking a measure or biomarker from concept through fit-for-purpose validation
  • Working knowledge of the regulatory bar for endpoints (FDA/EMA, biomarker qualification, validation frameworks such as DiMe V3)
  • Excellent communication skills, with a knack for turning scientific and regulatory rigor into clear product decisions

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