Principal Scientist, Early Pipeline Development
$108,500–$201,500 year
On-siteLa Jolla, California, United States
Job Summary
Lead and manage a 3-5 person downstream process team while providing technical support and SME knowledge to direct reports. Coordinate activities with upstream process and analytical teams, and develop strategies with Disease Areas to support early drug discovery from target selection through lead compound selection. Serve as a subject matter expert to transfer manufacturing process knowledge to the Technical Research & Development team and advance pipeline programs into clinical phases. Lead efforts to develop innovative, cost-effective downstream processes for next-generation AAV, manage multiple project workflows for timely delivery, and prepare written reports conforming to defined documentation practices.
Required Qualifications
- PhD in bioprocessing, biochemical engineering, gene therapy or a related field
- 3+ years of relevant process development experience in biotechnology/ pharmaceutical environment
- Experience in people management
- Knowledge of downstream purification processes including affinity and ion-exchange chromatography
- hands on experience with AKTA purification systems
- Technical proficiency
- creativity
- independent thoughts
- Effective communication skills
- Strong organization
- problem-solving skills
- attention to details
- Ability to work in a fast-paced and matrix environment
- Must be available for Onsite, San Diego, CA
Desired Qualifications
- Experiences in AAV gene therapy
- Experience with viral gene therapy
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