Principal Analytical Scientist (Automation)

Principal Analytical Scientist, Automation role in Regeneron’s Quality Control team, based on-site in Rensselaer, NY. Lead the design, implementation, and optimization of automated assay workflows across modern laboratory platforms (mass spectrometry, chromatography, bioassay, electrophoresis, ELISA). Mentor and develop junior and mid-level scientists, build team capability in analytical science and laboratory automation, set priorities, coordinate work, and track progress against milestones. Independently design and execute studies to evaluate emerging automation technologies and troubleshoot existing systems with limited supervision. Lead complex investigations into automated method performance, support verification activities, and drive continuous improvement. Transfer automated workflows to QC and partner functions by developing training materials, transfer plans, and acceptance criteria. Engage cross-functional collaborators and equipment vendors to evaluate new technologies and assess fit for QC applications. Prepare clear scientific reports, automation procedures, and SOPs; communicate findings, risks, and mitigation strategies to management and cross-functional teams. Requirements include hands-on programming/optimization of automated liquid handling systems (e.g., Hamilton/Venus, Andrew+/OneLab, or Cellario) and scripting in Python, R, or VBA; strong troubleshooting across analytical methods and automation hardware; ability to make independent decisions and mentor others. Preferred PhD or related advanced degree and experience in a cGMP or regulated environment are noted as desirable.