Molecular Design & DNA Nanotechnology Lead
$180,000–$200,000 year
On-siteEmeryville, California, United States
Job Summary
Design the DNA-origami actuator mechanism, including the charged drive plate and force-transmitting linkage, to achieve controlled nanometer-scale motion within a sub-200-nanometer footprint. Use coarse-grained molecular-dynamics simulation to predict mechanical behavior and iterate the design, while folding and optimizing DNA origami in the wet lab to anchor structures to the device surface. Own folding yield and quality control, preparing samples for characterization via atomic-force microscopy, cryo-electron microscopy, and single-molecule fluorescence. Lead a small, interdisciplinary founding team collaborating closely with device-physics, controls, and computational colleagues. This full-time role reports to Dr. Jeremy Barton and is based on site in Emeryville, CA.
Required Qualifications
- PhD in structural DNA nanotechnology, biophysics, bioengineering, chemistry, or a related field
- demonstrated DNA-origami design and folding experience
- Proficiency with DNA-nanostructure design tools and coarse-grained molecular-dynamics simulation (e.g., caDNAno, oxDNA)
- Hands-on wet-lab command of folding, gel and AFM quality control, and purification
- A track record of taking nanoscale structures from design through to characterized, functional devices
- Ability to lead a small interdisciplinary team and communicate across disciplines
- This is a full-time position
- This position is on site at our office in Emeryville, CA
- Some travel may be required from-to-time for in-person collaboration and work
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