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General MatterPosted 3 weeks ago

Mass Spectrometry Chemist

$100,000–$150,000 year

On-siteLos Angeles, California, United States

Full TimeBachelors DegreeStartup

Job Summary

Develop, optimize, and validate analytical methods for uranium isotopic analysis using isotope-ratio MS and ICP-MS systems. Perform isotopic sampling, sample preparation, and measurement workflows to support enrichment process monitoring and product certification. Operate, maintain, calibrate, and troubleshoot mass spectrometry instrumentation to ensure measurement accuracy, precision, and reliability. Integrate measurement systems with sample-handling workflows and support automation and process improvements. Collaborate with cross-functional partners to define analytical requirements and document methods while maintaining rigorous QA/QC protocols. Contribute to continuous improvement of analytical capabilities as General Matter scales production. This role requires on-site presence in Los Angeles, CA, or Paducah, KY, with extended hours and weekends as necessary.

Required Qualifications

  • Bachelor's degree in Chemistry, Radiochemistry or a related field, or equivalent experience
  • Hands-on laboratory experience with mass spectrometry techniques (ICP-MS, isotope-ratio MS, or similar)
  • Demonstrated ability to develop, troubleshoot, and optimize analytical methods and instrumentation
  • Strong problem-solving skills and attention to detail in data collection, analysis, and documentation
  • Evidence of exceptional ability — prior research projects, published work, or demonstrated technical contributions in analytical chemistry or instrumentation
  • Ability to obtain and maintain required security clearance and access authorization for work with nuclear materials
  • Ability to work on-site in Los Angeles, CA or Paducah, KY
  • Ability to work extended hours and weekends as necessary

Desired Qualifications

  • Experience with uranium isotopic analysis, nuclear materials characterization, or safeguards measurement techniques
  • Familiarity with TIMS, MC-ICP-MS, or other isotope-ratio mass spectrometry platforms
  • Prior work in a DOE national laboratory, NRC-licensed facility, nuclear fuel-cycle company, or instrumentation vendor environment
  • Experience in method validation, regulatory compliance (e.g., DOE, NRC, ISO standards), or quality assurance in analytical chemistry
  • Background in fast-paced, resource-constrained, or startup environments where autonomy and bias toward action are required
  • Strong communication skills and ability to collaborate across technical and operational teams

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