Manager, Commercial Supply Chain Operations
$107,700–$134,636 year
HybridWaltham, Massachusetts, United States
Job Summary
Plan, coordinate, and manage the progression of drug product through packaging into finished goods, ensuring finished goods runs are scheduled and executed promptly. Maintain finite production schedules at CDMOs to ensure on-time manufacture, testing, and release of batches aligned with forecasts. Own inventory management and control across the network of CDMOs and 3PLs, ensuring targets are met and inventory supports reliable supply. Manage shipping and logistics of product and material movements, coordinating shipments between manufacturing sites, warehouses, and 3PLs to ensure timely, compliant distribution. Serve as a first responder to temperature excursions and deviations, partnering with Quality to assess impact and drive disposition. Support commercial supply planning and provide inputs into the monthly Sales & Operations Planning process. Help implement tools and processes to scale the supply chain, including leveraging AI and agentic capabilities to automate workflows. Track and report key supply performance metrics to drive visibility and continuous improvement. Based at Zenas' Waltham, MA headquarters (hybrid).
Required Qualifications
- Bachelor's degree in Supply Chain, Engineering, Life Sciences, or a related field or equal combination education/experience
- Minimum of 5 years of hands-on supply chain experience in the pharmaceutical or biotechnology industry
- Direct experience in commercial supply planning
- Direct, hands-on experience in the biologics space planning and scheduling the production of drug substance (DS) and drug product (DP)
- Demonstrated, hands-on experience managing the packaging of finished goods and planning, coordinating, and tracking the DP-to-FG progression
- Hands-on experience with inventory management and control across CDMOs and 3PLs in a GMP environment
- Shipping and logistics experience, including cold-chain distribution and coordination of material movements across the network
- Experience developing agentic capabilities using AI tools (e.g., Claude) to build automation, tooling, and reporting solutions
- Advanced proficiency in Excel and Smartsheet
- Working knowledge of GMP requirements, batch release, and the impact of temperature excursions and deviations on commercial supply
- Strong written and verbal communication skills
- Ability to build and maintain strong relationships across internal functions and external partners
- Ability to work both independently and collaboratively in a fast-paced, matrixed environment
- Ability to manage ambiguity and help build new processes and tools from the ground up
- Ability to be based at Zenas' Waltham, MA headquarters (hybrid)
- Ability to travel and to work flexible business hours to support global partners and time zones as required (approximately 10–15%)
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