Head, Oncology Clinical Development - ADCs
$242,250–$403,750 year
On-siteZug, Zug, Switzerland or Waltham, Massachusetts, United States
Job Summary
Design and implement end-to-end clinical development strategy for a multi-tumor antibody drug conjugate asset, encompassing early- through late-phase trials, registrational approval, and initial market launch. Shape scientific positioning, champion novel approaches such as AI/ML and innovative trial designs, and lead strategic clinical advisory boards to inform portfolio decisions. Provide oversight across the asset program, serving as the senior clinical representative at key governance forums like the DRB and PIB to ensure rigorous decision-making. Partner cross-functionally with research, medical affairs, commercial, and precision medicine teams to align development and commercialization planning, while establishing continuous improvement in clinical standards and processes. Represent the Oncology Clinical Development organization externally at high-impact forums and advisory boards to drive competitive positioning and asset strategy.
Required Qualifications
- Medical degree (MD, MBBS, MBChB or international equivalent)
- Board certification/eligibility or registration in a primary or medical specialty
- Oncology drug development experience in the pharmaceutical industry
- Leadership experience of early- and focused late-phase oncology development programs from first-in-human through registrational studies and launch readiness
- Experience leading Antibody Drug Conjugate or other targeted oncology development programs
- Experience holding accountability for asset-level or portfolio-level clinical development strategy, governance, and execution
- Experience interacting with global health authorities and supporting regulatory submissions and approvals
- Experience leading global cross-functional teams in complex matrix environments
- Senior clinical and scientific leadership in early- and late-phase oncology drug development, including FTIH through registrational trials and launch readiness
- Strong ability to translate science and translational insight into differentiated clinical development strategies across disease areas and portfolios
- Proven capability to operate at portfolio level, balancing priorities, risk, and resources while maintaining asset-level rigor and accountability
- Credibility and effectiveness representing Clinical Development at senior governance forums, with strong executive presence and influence
- Advanced cross-functional and matrix leadership skills, with a natural connector mindset across research, development, medical, commercial, and precision medicine partners
- Openness to and fluency with innovative development approaches (e.g., AI/ML, novel trial designs, external and real-world data) where they add value
- Commitment to fostering a culture of scientific excellence, empowerment, inclusion, and continuous improvement in a complex global environment
- Minimum of two days a week on-site office presence at one of GSK's UK (Stevenage or London HQ); US (Collegeville, PA or Waltham, MA) sites; or Switzerland (Zug)
Desired Qualifications
- Board certification/eligibility or registration in medical oncology, hematology/oncology
- Strong experience in governance leadership, scientific narrative ownership, portfolio influence, and executive-level decision-making
- Experience in translational research, including the application of translational science to inform clinical development strategies and decision-making
- Experience utilizing innovative development approaches, including advanced analytics, AI/ML, real-world evidence, or novel trial design
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