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CapablePosted 1 month ago
EXPIRED

Founding Hardware Engineer (Synthesis)

$130,000–$190,000 year

On-siteSan Francisco, California, United States

Full TimeStartup

Job Summary

Design and develop automated peptide synthesis systems for high-throughput solid-phase peptide synthesis, engineering comprehensive fluidic architectures and advanced reaction modules. Create robust control systems to manage timed reagent addition, flow rates, and pressure while implementing automated recovery for faults. Prototype, test, and troubleshoot electromechanical systems including pumps, sensors, and embedded controllers, then assess hardware performance against chemical outputs like purity and yield. Collaborate with chemists to translate synthesis failure modes into hardware improvements and develop test protocols for subsystems. Integrate the synthesizer with analytical workflows such as HPLC and LC-MS to drive efforts toward faster, more reproducible peptide synthesis with minimal manual intervention.

Required Qualifications

  • substantive, practical experience in designing, building, or maintaining laboratory instrumentation
  • experience in automation systems
  • experience in microfluidic/fluidic devices
  • experience in electromechanical hardware for chemical or biological research applications
  • background in mechanical engineering
  • background in electrical engineering
  • background in chemical engineering
  • background in bioengineering
  • background in analytical chemistry
  • background in automation
  • background in robotics
  • equivalent hands-on experience to the listed backgrounds

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