Expert Pharma Discovery Biologist
$105,000–$115,000 year
On-site · South San Francisco, California, United States
Job Summary
Lead in vitro discovery biology across oncology programs from early target validation through candidate selection, spanning multiple therapeutic modalities. Contribute to target identification and prioritization by integrating literature, pathway biology, and emerging clinical and preclinical data to nominate and validate novel therapeutic targets. Design and execute cell-based assays to evaluate compound activity, including viability, proliferation, and apoptosis readouts across relevant tumor models. Drive mechanistic and signaling studies (e.g., Western blot, phosphoproteomics, pathway analysis) to characterize target engagement and mechanism of action. Lead target biology efforts including evaluation of target expression, antigen density, receptor internalization, intracellular trafficking, and target-dependent processing. Develop and optimize disease-relevant in vitro models (e.g., 3D culture systems, model generation, co-culture platforms) to characterize novel modalities and enable translational studies.
Required Qualifications
- PhD in Molecular Biology, Biochemistry or related field
- 0-2 years of industry or relevant postdoctoral experience in oncology drug discovery or targeted therapeutics research
- Excellent communication skills – verbal and written
- Works well both within a team and as an individual
- Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions
- The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery
- This is a day shift position (approx. 8a-5p local time)
- Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic
- Additionally, if you require a reasonable accommodation during the application or interview process, please let us know
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