Experienced Scientist (Neurodegeneration, Neuroinflammation, and Translational Biology)
$66,000–$106,000 year
On-site · Beerse, Flanders, Belgium
Job Summary
Experienced Scientist in Neurodegeneration, Neuroinflammation, and Translational Biology leading a 3-year VLAIO-funded program. Independently designs and executes complex in vitro experiments using human iPSC-derived neurons, astrocytes, and microglia, and conducts in vivo rodent studies to model Alzheimer’s disease. Applies molecular, cellular, and biochemical techniques (including immunohistochemistry, ELISA, proteomics) and prepares samples for omics analyses (bulk and single-cell transcriptomics, proteomics). Maintains rigorous ELN documentation, reports results to supervisors and project teams, and collaborates with cross-department and external partners. Requires strong scientific independence, ability to translate biological questions into robust experimental strategies, and hands-on work with humanized models. Preferred candidate will have Master’s plus 6+ years in pharma or a PhD in Neuroscience, FELASA B/C certification, and experience in translational research integrating in vitro and in vivo models.
Required Qualifications
- Master’s degree combined with demonstrated relevant experience and +6 years of work experience in pharma, or a PhD in Neuroscience may be considered
- Extensive hands-on experience with human iPSC-derived systems including neurons, astrocytes, and microglia
- In vivo experience with rodent models is a plus
- FELASA B certification is a minimal requirement, FELASA C certification is preferred
- Experience with single-cell sequencing approaches (e.g., scRNA-seq, single-nuclei RNA-seq) and downstream data interpretation is preferred
- Experience with live cell imaging (e.g. IncuCyte) and high content imaging is desired
- Expert in assay development, optimization and trouble shooting
- Experience integrating human in vitro and in vivo models in a translational research setting
- Strong analytical mindset with focus on data quality, reproducibility, and scientific rigor
- Ability to troubleshoot complex biological systems and adapt strategies
- Excellent communication and collaboration skills
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