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Denali TherapeuticsPosted 1 month ago

Director, Patient Support Strategy & Operations (Hybrid)

$204,000–$265,000 year

HybridSouth San Francisco, California, United States

Full TimeSenior LevelMedium

Job Summary

Lead the development and execution of patient support strategies for product launches and lifecycle management, including designing the Patient Access Hub for benefits investigation, prior authorization support, and case management. Establish Patient Assistance Program eligibility criteria, refine affordability frameworks, and define provider support pathways to streamline therapy initiation. Oversee day-to-day hub operations and vendor performance, managing relationships with specialty pharmacy partners to ensure high service quality and compliance. Monitor key performance indicators for time-to-therapy and HUB metrics while driving continuous improvement initiatives. Collaborate cross-functionally with Market Access, Marketing, Distribution, and Commercial teams to align access strategies with broader commercial goals and identify provider education needs. Ensure all programs operate in full regulatory and legal compliance through the development of standardized policies and governance frameworks.

Required Qualifications

  • BS/BA
  • 10+ years of experience in pharmaceutical/biotech patient support, access, reimbursement, hub operations, or specialty pharmacy
  • Demonstrated experience launching and managing patient support programs, particularly hybrid field/HUB models
  • Advanced degree preferred
  • Experience designing and managing patient affordability programs (copay, PAP)
  • Proven track record managing external vendors and service providers
  • Experience in specialty or rare disease therapeutic areas preferred
  • Strong expertise in patient support strategy, reimbursement, and HUB operations, with demonstrated ability to design and operationalize scalable, patient-centric programs
  • Working knowledge of compliance regulations related to copay and patient assistance programs
  • Strong understanding of U.S. payer systems, including Commercial, Medicaid, and Medicare (Part B and Part D), and medical vs. pharmacy benefit design
  • Proven cross-functional collaboration and stakeholder management skills
  • Analytical mindset with the ability to leverage data and insights to inform decision-making and continuously optimize program performance
  • Excellent communication skills with ability to influence across functions
  • Ability to manage multiple priorities in a fast-paced environment, with strong attention to detail and execution
  • Should be willing & able to travel 25-30%

Desired Qualifications

  • Advanced degree preferred

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