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Alnylam3 days ago

Associate Scientist II, Oncology

$67,600–$101,400 year

On-site · Cambridge, Massachusetts, United States

Type
Full Time
Level
Mid Level
Education
Masters Degree
Company size
Enterprise

Job Summary

Associate Scientist II in Oncology focused on supporting delivery research to advance Alnylam’s RNA therapeutics across multiple cancer indications. Responsible for designing, optimizing, and executing cell- and molecular-based experiments to evaluate developmental RNA candidates in relevant in vitro oncology models; conducting immunology-focused cell culture studies and functional assays; performing LNP-mediated transfection and electroporation in immune cell systems; carrying out multicolor flow cytometry for immune profiling and biomarker analysis; processing tissue samples and ex vivo models to assess target engagement and mechanism of action; analyzing and presenting findings within a multidisciplinary Oncology team. Emphasis on excellent documentation practices and collaboration within a fast-paced, onsite Cambridge, MA environment.

Required Qualifications

  • BS in Biology, Immunology, Molecular Biology, Bioengineering, or related field with 2-3 years or MS with 1+ years of industry or academic lab experience
  • Hands-on experience with primary immune cell and tumor-immune cell co-culture assays
  • Experience with nucleic acid-based approaches (RNAi, CRISPR, mRNA, plasmid DNA)
  • Proficiency in RT-qPCR, immunofluorescence, multi-color flow cytometry, Incucyte, and ELISA
  • Experience with high-throughput screening methods is highly desirable
  • This is an on-site lab-based role requiring extensive bench work and collaboration in a fast-paced environment
  • Must be a team player with good interpersonal skills
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$68k – $101k / yr

Associate Scientist II, Oncology · Alnylam

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