Associate Principal Scientist, Discovery Oncology
$159,600–$251,200 year
On-site · South San Francisco, California, United States
Job Summary
Associate Principal Scientist in Discovery Oncology leading conception, design, and execution of discovery-stage programs in South San Francisco. Role emphasizes designing and optimizing in vitro/ex vivo assays to elucidate mechanisms of action, balancing innovation with rigor, driving ideation and early-stage discovery for competitive oncology programs, and communicating strategy/results to internal teams and external audiences. Responsibilities include leading cross-functional collaboration, building external scientific presence through publications/conferences, and mentoring/scaling exploratory efforts to advance cancer therapies from target validation through early development. Qualifications include a Ph.D. with 4+ years in oncology drug discovery, strong tumor biology and immune-oncology expertise, proficiency in molecular/cellular biology and flow cytometry, and a track record of innovative research and leadership potential. Preferred: experience with multiple modalities (small molecules, mAbs, ADCs, TCEs) and in vivo mouse model data. The role also notes eligibility for ERP and a comprehensive benefits package, salary range, and relocation considerations, with visa sponsorship available and standard hiring process details.
Required Qualifications
- Ph.D. in Cancer Biology, Cell Biology, Pharmacology, Immunology, Biochemistry, or related discipline with four (4)+ years of oncology drug discovery experience
- Deep expertise in tumor biology and immune oncology
- Broad technical expertise in molecular and cellular biology, biochemistry, and analytical methods
- Hands-on multi-color flow cytometry and mechanistic cell-based assays
- Excellent communication and leadership potential
- Experience with therapeutic modalities (e.g., small molecules, mAbs, ADCs, TCEs)
- In vivo mouse model data experience to evaluate therapeutics
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