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Merck Sharp & Dohme Farmaceutica1 week ago

Associate Principal Scientist, Discovery Oncology

$159,600–$251,200 year

On-site · South San Francisco, California, United States

Type
Full Time
Level
Senior Level
Education
Doctorate Or Professional Degree
Company size
Unknown

Job Summary

Associate Principal Scientist in Discovery Oncology leading conception, design, and execution of discovery-stage programs in South San Francisco. Role emphasizes designing and optimizing in vitro/ex vivo assays to elucidate mechanisms of action, balancing innovation with rigor, driving ideation and early-stage discovery for competitive oncology programs, and communicating strategy/results to internal teams and external audiences. Responsibilities include leading cross-functional collaboration, building external scientific presence through publications/conferences, and mentoring/scaling exploratory efforts to advance cancer therapies from target validation through early development. Qualifications include a Ph.D. with 4+ years in oncology drug discovery, strong tumor biology and immune-oncology expertise, proficiency in molecular/cellular biology and flow cytometry, and a track record of innovative research and leadership potential. Preferred: experience with multiple modalities (small molecules, mAbs, ADCs, TCEs) and in vivo mouse model data. The role also notes eligibility for ERP and a comprehensive benefits package, salary range, and relocation considerations, with visa sponsorship available and standard hiring process details.

Required Qualifications

  • Ph.D. in Cancer Biology, Cell Biology, Pharmacology, Immunology, Biochemistry, or related discipline with four (4)+ years of oncology drug discovery experience
  • Deep expertise in tumor biology and immune oncology
  • Broad technical expertise in molecular and cellular biology, biochemistry, and analytical methods
  • Hands-on multi-color flow cytometry and mechanistic cell-based assays
  • Excellent communication and leadership potential
  • Experience with therapeutic modalities (e.g., small molecules, mAbs, ADCs, TCEs)
  • In vivo mouse model data experience to evaluate therapeutics
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$160k – $251k / yr

Associate Principal Scientist, Discovery Oncology · Merck Sharp & Dohme Farmaceutica

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